Dermatology Differential Diagnosis by Morphology

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Atrophic White Spots

1. Lichen sclerosis et atrophicus
2. Atrophic morphea
3. Lichen planus (atrophic varient)
4. Degos disease - Malignant atrophic papulosis

Acral Scleroatrophy

Epidermal Atrophy

1. Steroid induced atrophy
2. Senile atrophy
3. Mycosis fungoides
4. Poikilodermas
   • Poikiloderma atrophicans vasculare ( +/- Reticulosis [ e.g. M.F. ] )
   • Poikiloderma of Civatte
   • Poikiloderma congenitale
   • Rothmund-Thomson syndrome
   • Dermatomyositis
   • Lupus erythematosus
   • Lichen planus erythematosus
   • Scleroderma (rare)
5. Acrogeria / Progeria / Werner's syndrome

Dermal Atrophy

1. Anetoderma
   • Jadassohn-Pellizari type (Inflammatory precursor)
   • Schwenniger-Buzzi type (No precursor, arises de novo)
2. Atrophoderma
   • Idiopathic atrophoderma of Passini and Pierini
   • Follicular atrophoderma - associated with:
     • Bazex's syndrome
     • Chondrodysplasia punctata
3. Striae
4. Acrogeria / Progeria / Werner's syndrome

Subcutaneous atrophy

1. Lipoatrophy / Lipodystrophy
   • Insulin or steroid (triamcinolone) injections
   • Subcutaneous fat necrosis
   • Panniculitides
   • Panatropy of Gower
   • Romberg hemiatrophy
   • Congenital total lipodystrophy (Lawrence-Seip syndrome)
   • Acquired generalized lipodystrophy
   • Acquired partial face-sparing lipodystrophy (Dunnigan syndrome)
   • Partial lipodystrophy (C3 nephritic factor)
2. Senile atrophy
3. Werner's syndrome

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June, 1996

Dept. of Dermatology / University of Iowa /

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Last updated November 12, 1996