Dept. of Dermatology - University of Iowa College of Medicine

Dermatology Differential Diagnosis by Morphology

Tumor Lesions

Differential by Color

Painful Dermal Tumors
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Tumor Differential by Color

Brown

Black - Grey

Blue

Pink - Red - Purple

Skin Colored - Yellow - Fawn - Orange

Brown

  1. Malignant melanoma - Examples at the Image Database.
  2. Juvenile melanoma (Spitz nevus)
  3. Melanocytic nevus
  4. Pyogenic granuloma (brown to red)
  5. Seborrheic keratosis
  6. Comedone
  7. Basal cell carcinoma - More examples at the Image Database.
  8. Acanthoma (brown to pink)
  9. Histiocytoma
  10. Skin tags (Acrochordons)
  11. Clear cell acanthoma
  12. Trichofolliculoma
  13. Actinic keratosis
  14. Squamous cell carcinoma
  15. Paget's disease
  16. Nevus of Ota (brown to blue)
  17. Neuroma (brown, pink or purple)
  18. Leiomyoma (dusky brown-pink-red)
  19. Hidradenoma papilliferum (reddish-brown when ulcerated)
  20. Sarcoidosis - Examples at the Image Database.

Black-Grey

  1. Melanocytic nevus
  2. Blue Nevus
  3. Malignant melanoma - Examples at the Image Database.
  4. Seborrheic keratosis
  5. Basal cell carcinoma - Examples at the Image Database.
  6. Paget's disease (pink-grey-yellow)
  7. Hematoma
  8. Thrombosed plantar wart
  9. Apocrine hidrocystoma (blue-grey-black)
  10. Bowen's disease
  11. Granuloma telangiectaticum (blue-black)
  12. Eccrine hidrocystoma

Blue

  1. Blue nevus
  2. Malignant melanoma - Examples at the Image Database.
  3. Neurofibroma
  4. Histiocytoma
  5. Thrombosed plantar wart
  6. Apocrine hydrocystoma (blue-grey-black)
  7. Nevus of Ota (blue-brown)
  8. Granuloma telangiectaticum (blue-black)
  9. Kaposi's sarcoma (dark blue or purple)
  10. Lymphangiosarcoma of Stewart and Treves (dusky blue to red)
  11. Eccrine hidrocystoma

Pink - Red - Purple

  1. Juvenile melanoma (Spitz nevus)
  2. Pyogenic granuloma
  3. Malignant melanoma - Examples at the Image Database.
  4. Hemagioma (purple)
  5. Keratoacanthoma (flesh colored to red)
  6. Histiocytoma
  7. Eccrine poroma (acrospiroma) (pink to livid red)
  8. Hidradenoma papilliderum (ma be reddish brown)
  9. Dermal cylindroma (pink to red)
  10. Bowen's disease
  11. Erythroplasia of Queyrat
  12. Paget's disease
  13. Dermatofibrosarcoma (re or flesh colored)
  14. Fibrosarcoma (red or purple)
  15. Pseudosarcoma (red and granulomatous)
  16. Trichoepithelioma (pink-yellow)
  17. Glomus tumor
  18. Malignant angioepithelioma
  19. Lymphangiosarcoma of Stewart and Treves (dusky blue to red)
  20. Neuroma (pink to purple to brown)
  21. Neurolemmoma (pink to grey to yellow)
  22. Leiomyoma (pink-grey-dusky brown)
  23. Leiomyosarcoma (red)
  24. Hidradenocarcinoma (red to violet)

Skin Colored - Yellow - Fawn - Orange

  1. Basal cell carcinoma - Examples at the Image Database.
  2. Seborrheic keratosis
  3. Sweat gland nevus (orange - red - brown)
  4. Trichoepithelioma (pink - yellow)
  5. Sebaceous adenoma (yellow)
  6. Sebaceous carcinoma (yellow - orange)
  7. Milium (white - yellow)
  8. Steatocystoma multiplex (yellow)
  9. Syringoma (yellow - mauve - translucent)
  10. Actinic keratosis (yellow)
  11. Neurolemmoma (pink - grey - yellow)
  12. Eccrine spiradenoma (flesh colored)
  13. Syringoma papilliferum (flesh colored)

Painful Dermal Tumors

  1. Angiolipoma
  2. Angioleiomyoma
  3. Eccrine spiradenoma
  4. Glomus tumor
  5. Neuroma
  6. Neurolemmoma
  7. Leiomyoma

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June, 1996
Dept. of Dermatology / University of Iowa /
Last updated November 12, 1996